Genetic influence on medicines

Do you experience many of the side effects described in the package insert? Or does a medicine actually do less than you expected? That may be due to your genes, because everyone is unique, after all.

meamedica.com pharmacogenetic test

The meamedica.com personal medicine test, a medication response test (also known as a pharmacogenetic test), determines how your body breaks down medicines based on your DNA. With these results, your healthcare provider can make better informed decisions about which medicine suits you best and at what dose/strength.

 
human body
Personal Medicine

High accuracy
Your doctor/pharmacist can use it to adjust the dosage of medication.


Detailed medicine passport
It determines the activity of 28 genes that play a role in the processing of medicines.


Clear reporting per gene
With indication of your sensitivity per medicine.
available early 2021!

Your DNA influences the result

Your DNA determines how you respond to medication. Your genes have a huge influence on the way a medicine is taken up, divided into the body and broken down again. They can therefore be responsible for the differences in response to a medication. Your genes determine whether your body breaks down a drug too slowly, normally or too quickly, which can result in unpleasant side effects or no effect at all.

A pharmacogenetic test shows the activity of the different involved enzymes and gives information about the type of medicine that suits you and the corresponding dose.


Effect of genes on medication in certain conditions

Depression and anxiety

More than one million people use an antidepressant, although it does not work sufficiently well in about 30 to 50% of the cases. The search for the right agent in the right dosage can take months. During that time, the side effects are often violent, which seriously affects self-confidence, or confidence in the doctor and in the treatment.

Do you recognize this and do you have problems finding the right medicine for depression or anxiety disorder? Then take a DNA test. Your DNA regulates how your body deals with medicines. Our DNA test shows the activity per gene and which medicines are processed by each gene. This way you can immediately see which medicine may be more appropriate.

Psychosis

Medicines are usually an important part of the treatment of psychosis. These medicines are called 'antipsychotics'. They affect the functioning of nerve cells in the brain. Antipsychotics help you to get out of psychosis. Antipsychotics have no curative effect; they do not eliminate the cause of the psychosis or solve underlying problems. The medication ensures that anxiety and agitation are muffled. This can help you regain control of your life. Antipsychotics often come with many side effects and it can often take a long time before it is clear whether they also help against the psychotic symptoms.

Do you have trouble finding a suitable medicine? Then take a DNA test. Your DNA regulates how your body deals with medicines. Our DNA test shows the activity per gene and which medicines are processed by each gene. This way you can immediately see which medicine may be more appropriate.

High blood pressure

High blood pressure is a leading cause of cardiovascular disease, heart failure, strokes, kidney problems and brain damage. In addition to factors such as diet and smoking, blood pressure is largely (30% to 60%) determined by hereditary predisposition. Your doctor or general practitioner determines in consultation with you which medicines you will receive to treat high blood pressure. There are different types of medication to lower blood pressure.

You will often be prescribed more than one kind. That often works better and you have less chance of side effects. Unfortunately, only a small number of patients with hypertension control blood pressure with the appropriate drug therapy. Research into differences in DNA can then be used as a tool to improve the treatment of blood pressure.

High cholesterol

Statins are indicated for the prevention of cardiovascular disease and are among the most commonly prescribed classes of medication. However, not all patients respond favorably to statins, and some do not achieve their cholesterol lowering goals. In addition, a significant number of patients experiences adverse effects. Muscle inflammation, muscle weakness, and liver abnormalities are the most commonly reported side effects of statins, often leading to poor compliance or statin discontinuation.

A pharmacogenetic test, such as the meamedica.com personal medicine test, can provide an opportunity for the patient to weigh up the potential benefits against the potential risks of a statin together with his practitioner. The choice of a statin and its dosage can be adjusted to your DNA.





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