ISO 27001

The independent platform for sharing experiences with medication

The independent platform for sharing experiences with medication

A professional outlook on Olanzapine

Bojan Nikolik

Bojan Nikolik

6e jaars farmaciestudent

5written expert review(s)


 psychosis / schizophrenia - antipsychotics Effectiveness: 5

Olanzapine (Zyprexa)

Condition for which this medication is usually prescribed


Short description of this condition

Schizophrenia is a psychological disorder that is characterized by abnormal social and emotional behaviour, and disturbed thinking processes. The disorder expresses itself as a reduced ability to distinguish reality from fantasy, particularly with short episodes of hearing voices, suspicious delusions (paranoia) and unconnected thinking processes, or in other words psychosis.

Effect of this medication

Olanzapine is an atypical antipsychotic. It slows down the effects of serotonin and dopamine in the brain, so that anxiety and other symptoms of psychosis decrease. For as long as you take the medicine, the chance of psychosis recurring is reduced.

Advice on this condition

Do not just stop taking this medicine. When stopping too early or reducing the use of this drug too quickly, there is a strong possibility that psychosis may return alongside the risk of withdrawal symptoms.

Common side effects

Weight gain, drowsiness/fatigue, reduced libido, unusual or uncontrollable movements.

Advice with regard to these side effects

Weight gain and increased appetite are common side effects of this medicine, which is why it is important that you pay extra attention to your diet. Your feelings of drowsiness and fatigue will reduce as you become accustomed to the medicine. Possible unusual or uncontrollable movements, such as not being able to sit still, facial muscle contractions or muscle stiffness will pass quickly. If you still experience any of these after a few days, discuss it with your doctor as it may be that the dose can be reduced or you can switch to another medicine.

Any other expert information?

Olanzapine is also prescribed for other psychological disorders, in particular mania, anxiety, tics and posttraumatic stress disorders.