ISO 27001

The independent platform for sharing experiences with medication

The independent platform for sharing experiences with medication

A professional outlook on Sertraline

Arjen Walstra

Arjen Walstra


5written expert review(s)


 depression - antidepressant ssri Effectiveness: 3


Condition for which this medication is usually prescribed


Short description of this condition

Depression is a condition in which you feel negative and without motivation. Depression is not the same as having a bad day and is more often to do with a chemical imbalance in the brain. A doctor will be able to help you tell the difference between 'feeling depressed' and depression.

Effect of this medication

The cause of depression is often unclear or unknown. Depression occurs most often because of a chemical imbalance in the brain, but can also be caused by events or bereavement. One of the chemicals in the brain that can be affected by depression is called serotonin. Sertraline belongs to a group of medicines which can influence serotonin. It is most likely that the positive effect of sertraline on your mood is because it reduces the amount of serotonin in the brain.

Advice on this condition

If you want to stop taking sertraline then you must do so slowly over a period of weeks in order to avoid withdrawal symptoms and side effects.

Common side effects

Insomnia, nausea.

Advice with regard to these side effects

It is possible that the side effects will disappear by themselves over time.

Any other expert information?

Just like some other anti-depressants, sertraline should be prescribed with caution to those under the age of 24. In comparison to adults, there is a higher likelihood of suicide due to the use of anti-depressants in those up to the age of 24. Children under the age of 18 are 1.4% more likely to commit suicide when taking anti-depressants. Young adults between the ages of 18 and 24 are at a slightly lower increased risk, of 0.5%.