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The independent platform for sharing experiences with medication

The independent platform for sharing experiences with medication

A professional outlook on Omeprazole

Arjen Walstra

Arjen Walstra


5written expert review(s)


 heartburn - proton-pump inhibitors (ppis) Effectiveness: 4

Proton pump inhibitor omeprazole

Condition for which this medication is usually prescribed

Upset stomach

Short description of this condition

Some people suffer from increased production of stomach acid. This increased production of stomach acid can lead to complaints such as heartburn and in serious cases is one of the risk factors of bleeding (haemorrhaging) in the stomach.

Effect of this medication

Omeprazole belongs to a group of medicines called proton pump inhibitors. Omeprazole binds to the cells which produce stomach acid and prevents them from producing stomach acid. The acidity of the stomach is then reduced. This means that heartburn and the risk of bleeding in the stomach is reduced. However, stomach acid is also essential – it plays a role in the defence against bacteria. These bacteria are often not able to survive in acidic environment.

Common side effects

Stomach and bowel complaints, headaches.

Advice with regard to these side effects

Taking this medicine after eating will help with stomach and bowel pain. Omeprazole is effective for more than 24 hours so it doesn't necessarily need to be taken again before your next meal.

Any other expert information?

Over time, more information is becoming available about the chronic use of omeprazole. It can lead to a vitamin B12 deficiency and research has shown that there is also a greater risk of developing osteoporosis. If you only take omeprazole for heartburn, you could also avoid certain foods and drink less alcohol. Acidic and fatty foods, just as drinking alcohol, can affect heartburn.